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Finding guanine quadruplexes in DNA using decision trees
Kotrys, Kryštof ; Šťastný, Jiří (referee) ; Kaura, Patrik (advisor)
This bachelor’s thesis is focused on creating a functional decision tree model for detection of guanine quadruplexes in the DNA. The first part of the thesis summarizes theoretical knowledge in the fields of local DNA structures, computational prediction methods of guanine quadruplexes and decision trees. The second part describes the creation of a decision tree model, followed by a statistical comparison of the results with the G4Hunter algorithm.
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Implementation of local DNA structures analysis tool
Kaura, Patrik ; Trenz, Oldřich (referee) ; Šťastný, Jiří (advisor)
This diploma thesis is focused on the description and implementation of the API wrapper application, which works on top of computational core ibp bioinformatics. The first half of the thesis is focused on the summary of basic knowledge in the field of DNA research, as well as the specification of the problem and description of selected technologies. The other half deals with the actual implementation, distribution, and evaluation of application applicability on specific DNA sequences.
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Finding guanine quadruplexes in DNA using decision trees
Kotrys, Kryštof ; Šťastný, Jiří (referee) ; Kaura, Patrik (advisor)
This bachelor’s thesis is focused on creating a functional decision tree model for detection of guanine quadruplexes in the DNA. The first part of the thesis summarizes theoretical knowledge in the fields of local DNA structures, computational prediction methods of guanine quadruplexes and decision trees. The second part describes the creation of a decision tree model, followed by a statistical comparison of the results with the G4Hunter algorithm.
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|
|
Implementation of local DNA structures analysis tool
Kaura, Patrik ; Trenz, Oldřich (referee) ; Šťastný, Jiří (advisor)
This diploma thesis is focused on the description and implementation of the API wrapper application, which works on top of computational core ibp bioinformatics. The first half of the thesis is focused on the summary of basic knowledge in the field of DNA research, as well as the specification of the problem and description of selected technologies. The other half deals with the actual implementation, distribution, and evaluation of application applicability on specific DNA sequences.
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